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We released WPF Studio 2012.1 build 561 yesterday afternoon but noticed that there was an issue when running the controls on the .NET 4.5 RC. In yesterday's original build 561 release, we had made various security tweaks and tried to restore the use of AllowPartiallyTrustedCallersAttribute in the product assemblies. While it worked fine on .NET 4.0 machines, it was causing an exception on machines with .NET 4.5 RC installed. It's not clear if that is a bug in .NET 4.5 or not, but considering many of our customers do have .NET 4.5 RC installed, we chose to redeploy build 561 without AllowPartiallyTrustedCallersAttribute so that it works everywhere properly.
The redeploy went live around midnight last night. If you had downloaded build 561 yesterday, please download the build again from our site to ensure you have the hotfix. Sorry for the inconvenience.